Mitochondrial Population Structure in MGH-AIS
(A) Relationship between European mitochondrial haplogroups. Different colors identify haplogroups descending from the same ancestral haplogroup (preHV = green, JT = light blue, N = orange).
(B) mtPCs 1 and 2 recapitulate haplogroup information in European Americans enrolled in the MGH-AIS. Colored contours identify haplogroups as in (A). Colored dots convey information about haplogroup assignment for each individual.
(C) Plotting mtPCs 1 and 3 further separates haplogroups K, I, and WX from U as compared to the plot in (B). Colored dots convey information about haplogroup assignment for each individual as in (B).
(D) Tridimensional plot of mtPCs 1–3 in European Americans enrolled in MGH-AIS assigns individuals to clusters that recapitulate mitochondrial haplogroup assignment.