Table 1.
Clinical Characteristics of the Pedigree Members with Kir3.4-Gly387Arg or Sudden Death
|
Subject Information |
Symptom |
Electrocardiogram |
Echocardiogram |
|||||
|---|---|---|---|---|---|---|---|---|
| Identity | Gender | Age (Years) | Recurrent Syncope | Recurrent Palpitation | QTc (ms) | Other Findings | LVEDD (mm) | LVEF (%) |
| I-2 | F | 72a | + | + | NA | Permanent AF | NA | NA |
| II-2 | F | 67a | + | + | 490 | AT, TdP | NA | NA |
| II-4 | F | 66 | + | + | 560 | Permanent AF | 60 | 50 |
| II-8 | F | 64 | + | + | 520 | Persistent AF | 50 | 54 |
| II-9 | M | 60 | + | + | 450 | AT | 40 | 57 |
| II-12 | F | 48 | + | + | 470 | − | 49 | 64 |
| II-13 | M | 7 daysa | + | NA | NA | NA | NA | NA |
| III-3 | M | 48 | + | + | 450 | − | 49 | 71 |
| III-5 | M | 40 | − | + | 430 | − | 52 | 64 |
| III-15 | F | 38 | + | + | 470 | − | 40 | 61 |
| III-22 | F | 35 | − | + | 460 | − | 39 | 65 |
| IV-1 | F | 13 | + | + | 460 | − | 36 | 72 |
The following abbreviations are used: QTc, QT interval corrected for heart rate; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; +, present; −, absent; NA, not available or not applicable; AF, atrial fibrillation; AT, atrial tachycardia; TdP, torsades de pointes.
a
Age at death.