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. 2010 Nov 11;13(1):44–53. doi: 10.1208/s12248-010-9238-5

Table III.

Relative Bias and Relative Root Mean Square Error (in %) for Standard Error Estimates for All Studied Scenarios

Simulation Standard error estimates Relative bias (%)
Relative RMSE (%)
Scenario ω 2 se(α 1) se(α 2) se(α 3) se(β 1) se(β 2) se(ω 2)
A 4 0.00 0.13 0.18 −0.67
0.14 0.15 0.20 0.87
10 −0.23 −0.25 0.17 −1.28
0.30 0.27 0.20 1.43
40 −0.30 −0.10 −0.02 −0.51
0.39 0.24 0.19 0.93
B 4 0.35 −0.36 0.01 −0.69
0.44 0.42 0.46 1.39
10 −0.29 −0.26 −0.10 −0.40
0.49 0.36 0.49 1.40
40 −0.73 −0.53 −0.61 −1.56
0.96 0.66 1.01 2.34
C 0.5 −0.17 −0.12 −0.09 −4.19
0.43 0.37 0.69 6.98
2 0.02 −0.73 0.70 −2.03
0.35 0.82 0.98 3.06
4 0.01 −0.46 −0.77 −1.56
0.32 0.59 1.1 2.19
10 −0.50 0.52 −1.23 −2.01
0.68 0.66 1.43 2.76
40 −1.58 −0.91 −0.28 −4.27
1.73 1.09 1.01 4.99
D 4 −0.02 0.06 −0.36 −0.08 1.27 −0.79
0.14 0.11 0.37 0.28 1.29 0.97
E 0.5 −1.69 −0.03 0.33 −1.79 −2.48 −5.78
1.91 0.39 0.51 2.62 2.61 7.42
4 −0.73 −1.06 0.64 −0.11 3.37 −1.73
0.89 1.18 0.77 0.99 3.64 2.52
40 −1.27 −0.63 −0.36 −0.35 −0.43 −2.36
1.43 0.84 0.66 1.09 2.35 3.39

These results correspond to the visual ones shown in the right panel of Fig. 2a–e