Figure 1.
Effect of neutrophil depletion on the number of lung DCs in response to Aspergillus. Number of lung neutrophil (A), inflammatory DCs (B), mucosal DCs (C) and plasmacytoid DCs (D) are shown at various times after challenge with killed Aspergillus hyphae in animals with Ab-mediated neutrophil depletion and mice treated with isotype control Ab. Data shown represent mean ± SEM; n = 20 mice per group per time point pooled from 4 independent experiments for panels A–B and n = 8 mice per group per time point pooled from 2 independent experiments for panels C–D. Time 0 represents unchallenged animals; *, p < 0.05 comparing trend between the two groups over time.