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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: Clin Cancer Res. 2010 Oct 5;16(22):5402–5413. doi: 10.1158/1078-0432.CCR-10-1491

Fig. 1.

Fig. 1

MSH6 mismatch repair deficiency. Top, isolated loss of MSH6 expression by immunohistochemistry; left shows normal expression of MSH2, and right shows loss of MSH6 expression. Middle, MSI testing in case 75 showing instability for all five mononucleotide repeats. Penta D and Penta D correspond to pentanucleotide repeats used as controls. Bottom, MSH6 sequence electropherogram showing the p.S1279P mutation.