Figure 2.

T. whipplei modulates the cellular content of pro- and anti-apoptotic mediators. MDM were infected with T. whipplei (MOI 50 : 1) for 4 h, washed and incubated for 24 h. Cell lysates were applied on a human apoptosis protein array. The average density of duplicate spots representing each pro-apoptotic (a) and anti-apoptotic (b) proteins was expressed in arbitrary units (AU). Significant changes in protein expression after T. whipplei infection were determined by two-way ANOVA (^*P<0.05; ^***P<0.001)