. Author manuscript; available in PMC: 2011 Feb 2.

Published in final edited form as: Antivir Chem Chemother. 2010 Oct 28;21(1):1–14. doi: 10.3851/IMP1680

Table 1.

Properties of nanogels and Nano-NRTI

	Network	Total N content, mmol/mg^*	Hydrodynamic diameter, nm^†	NTP content in Nano-NRTIs,%^‡
	Network	Total N content, mmol/mg^*	Hydrodynamic diameter, nm^†	AZTTP	ddITP	CTP
NG1	PEG-cl-PEIss	2.5	175 ± 10 (90 ± 3)	23	8.5	13.5
NG2	F68-cl-PEIss	2.1	190 ± 7 (120 ± 9)	16	6.5	11
NG3	starPEG-g-PEI	1.8	150 ± 9 (115 ± 5)	21	11.5	15.5
NG4	PAMAM-PEI-g-PEG	2.2	160 ± 7 (100 ± 6)	12	5.5	13
AP-NG1	ApoE-NG1	1.9	197 ± 11 (105 ± 5)	16	8	9.5

Determined by elemental analysis of nanogels

^†

Measured by DLS (water, pH 7, concentration 0.1%). Data for NTP-loaded nanogels are shown in brackets

^‡

Determined by UV absorbance of aqueous solutions of NTP-loaded nanogels and free drugs at 260 nm