Figure 2.

Description of different metrics used in this study. In the example shown, we observe five different domain types. The abundance of a domain type is defined as the number of occurrences of the individual entity within the species (e.g. domain type B has an abundance of two). The versatility is defined as the number of different direct adjacent N- or C-terminal neighbors. We distinguish between N- and C-terminal partners (e.g. the versatility of domain type C is three). A bigram is a set of two directly adjacent domains, and we also consider two entities of the same domain a bigram (e.g. we observe nine different bigram types in the proteome, of which two have an abundance of three [right panel]).