Table 2.
Structural organization of the amino acid sequence in the circumsporozoite (CR) of Colombian alleles
| Strains | Central repetitive regions | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | |
| PNG* | 1 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 |
| Vc01 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Vc02 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Vc03 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 2 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – | – | – |
| Vc04 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 4 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 5 | – | – | – |
| Vc05 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 2 | 4 | 4 | 2 | 2 | 2 | 2 | 5 | – | – | – |
| Ch01 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ch02 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ch03 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 |
| Ch04 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ch05 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ca01 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ca02 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ca03 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ca04 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Ca05 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Nr01 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 3 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 7 | 2 | 5 | – |
| Nr02 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 4 | 2 | 2 | 4 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Nr04 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 8 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 5 | – | – | – |
| Nr05 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – |
| Pt01.3 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 5 | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Pt01.7 | 6 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – | – | – | – |
| Pt02.1 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – | – | – |
| Pt02.2 | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 5 | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Pt03 | 6 | 2 | 2 | 2 | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 2 | 2 | 5 | – | – | – |
| Pt04.5 | 1 | 2 | 2 | 2 | 2 | 5 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Sal I† | 9 | 9 | 9 | 9 | 10 | 9 | 9 | 9 | 9 | 10 | 10 | 9 | 10 | 9 | 10 | 9 | 10 | 10 | 11 | 11 | |
| Nr03 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 9 | 10 | 10 | 10 | 12 | |
| Pt04.1 | 9 | 9 | 9 | 10 | 10 | 9 | 9 | 9 | 9 | 10 | 10 | 9 | 10 | 9 | 10 | 9 | 10 | 10 | 11 | 11 | |
1‡ = EDGAGNQPG 3 = ANGADDQPG 5 = ANGAGGQAA 7 = ANGAGGQPG 9 = GDRADGQPA 11 = GDRAAGQAA
2 = ANGAGNQPG 4 = ANGAGDQPG 6 = EDGAGDQPG 8 = ANGADNQPG 10 = GDRAAGQPA 12 = GNGAGGQAA
†
Comparison of central repeats of VK210-type Colombian alleles with Sal I reference sequence.
‡
Numbers correspond to repeat type sequence located in repeat position 1–21.