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. 2011 Feb 4;84(Suppl 2):71–77. doi: 10.4269/ajtmh.2011.10-0085

Table 2.

Probability of sera used in the potency assay to retain transmission-blocking (TB) or enhancing activities upon dilution

TB categories (% reduction)* Probability of sera to retain TB activity
90–100 50–89 0–49 < 0
90–100 0.06 0.02 0.00 0.00
50–89 0.43 0.40 0.05 0.06
0–49 0.24 0.36 0.26 0.39
< 0 (enhancing) 0.27 0.22 0.69 0.55
*

Categories of transmission-blocking activity to classify the percentage reduction of infected mosquitoes and oocyst count.

Analysis of the probablity of 37 sera at 2-fold dilution (1:2 to 1:64) to retain the ability of blocking at any of the TB categories.

Classification of percentage of transmission–blocking activity in 37 undiluted sera.