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. Author manuscript; available in PMC: 2011 Feb 2.
Published in final edited form as: Braz J Med Biol Res. 2010 Mar 6;43(4):377–389. doi: 10.1590/s0100-879x2010007500014

Figure 3.

Figure 3

Increased anti-heart antibodies in mice with post-ischemic heart failure. A, Semi-quantitative immunoblot of IgM and IgG reactivity to autologous heart extract was scored for individual control (Ct), sham-operated (Sh) and heart failure (HF) mice 7 weeks after surgery. B, Densitometric profiles of serum IgM and IgG immunoreactivities of individual control (black lines) and HF (red lines) mice to heart extracts are shown. Reactivity intensities (absorbance) and migration distances are reported as arbitrary units. The values of the individual IgM or IgG immunoreactivity intensity (peak value) were submitted to principal component analysis. Scores of the resulting first two principal components of the individual Ct and HF mice are shown in two-dimensional plots in the insets: control (open squares) and heart failure mice (black squares). Data are reported as means ± SD of at least 5 mice per group. P < 0.05, HF mice vs control mice (Kruskal-Wallis test).