Figure 3.

At 48 h after application of drugs to primary human keratinocyte cultures. (a) ATP (1–10 μM) and UTP (100 μM) cause an increase in cell number, whereas ATPγS (100–500 μM) and ATP (100 μM) cause a significant decrease. Results represent the mean of eight experiments. ^*P<0.001 compared with that of control. (b) 2MeSADP (500 μM) causes a significant increase in cell number. Results represent the mean of eight experiments. ^*P<0.05 compared with that of control. (c) BzATP (100–500 μM) causes a significant decrease in cell number. Results represent the mean of nine experiments. ^*P<0.001 compared with that of control. Error bars represent mean±S.E.M (reproduced with permission from Greig et al.¹⁴⁰)