Table 5. Frequencies of molecular markers of resistance to SP and AQ at baseline and at the end of the intervention period in intervention and control arms.

Molecular Markers	Baseline		Postintervention					Baseline Versus Overall Postintervention p-Value
			IPTc		Placebo
	n	Percent Mutant	n	Percent Mutant	n	Percent Mutant	p-Value
DHFR 51	48	62.5	78	75.6	148	66.2	0.144	0.35
DHFR 59	48	60.4	78	76.9	148	59.5	0.009	0.50
DHFR 108	41	78.0	76	78.9	139	71.2	0.217	0.58
DHPS 437	47	38.3	83	67.5	165	43.6	<0.001	0.09
DHPS 540	45	0	82	7.3	165	3.6	0.205	0.82
Triple DHFR mutations	41	58.5	76	69.7	139	54.0	0.024	0.90
Quadruple mutants (triple DHFR + DHPS 437)	41	22.0	75	53.3	139	28.1	< 0.001	0.07
Pfcrt-76	46	80.4	79	84.8	156	75.0	0.085	0.25
Pfmdr1-86	46	45.6	76	36.8	156	34.6	0.739.	0.19

n =  number of participants with parasitaemia at blood smear tested.