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. 2011 Feb;18(2):96–102. doi: 10.1101/lm.1949711

Figure 1.

Figure 1.

Facilitation by 1- or 10-min 5-HT in isolated cell culture. (A) The experimental preparation. (B) The general protocol (see the text for details). (C) Examples of EPSPs in representative experiments with 1-min 5-HT, 10-min 5-HT, or test-alone control. (D) The average change in the EPSP in all of the no-drug (control) experiments with 1-min 5-HT (n = 18), 10 min, 10 μM 5-HT (n = 18), 10 min, 20 μM 5-HT (n = 20), and test-alone control (n = 18). There was a significant overall effect of group (F(3,70) = 31.76, P < 0.001) in a two-way ANOVA with one repeated measure (time). The data have been normalized to the value on the pretest in each experiment, and the error bars indicate the SEM.