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. Author manuscript; available in PMC: 2011 Feb 2.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Dec 24;877(3):285–290. doi: 10.1016/j.jchromb.2008.12.024

Table 6.

Potential concomitant medication interferences

Medium validation sample (1500 ng/mL) was spiked with potential concomitant drugs at 5000 ng/mL and processed as usual.

Drugs Peak area ratio (INH/IS) STD %CV %Dev due to matrix effect

replicate 1 replicate 2 replicate 3 mean
control 3.64 3.74 3.67 3.68 0.05 1.35
EFV 3.64 3.44 3.68 3.59 0.13 3.55 -2.49
ZDV 3.62 3.51 3.55 3.56 0.05 1.52 -3.35
TFV 3.79 3.78 3.67 3.75 0.07 1.76 1.85
ATV 3.78 3.77 4.09 3.88 0.19 4.80 5.42
LPV 3.69 3.87 3.94 3.83 0.13 3.43 4.18
RTV 3.61 3.87 3.70 3.73 0.13 3.46 1.23
NFV 4.22 4.01 4.22 4.15 0.12 2.89 12.8
NVP 3.31 3.37 3.47 3.39 0.08 2.40 -7.98
IDV 3.93 3.87 3.88 3.89 0.03 0.89 5.82
APV 3.88 3.67 3.66 3.74 0.13 3.39 1.52
ABV 3.52 4.03 4.00 3.85 0.29 7.45 4.67
SQV 3.73 3.88 3.76 3.79 0.08 2.07 2.94