Table 2.
Comparison of bacterial composition from inflamed and non-inflamed tissue within individual IBD patients using ∫-LIBSHUFF, unweighted and weighted UniFrac, the parsimony P-test and RDP Library Compare.
| Crohn's Disease Patients | Ulcerative Colitis Patients | |||||||||||
| CD1 | CD2 | CD3 | CD4 | CD5 | CD6 | UC1 | UC2 | UC3 | UC4 | UC5 | UC6 | |
| ∫-LIBSHUFF | * | ** | ** | n/s | * | n/s | * | * | *** | ** | * | ** |
| UW UniFrac | *** | *** | *** | n/s | *** | *** | *** | *** | ** | *** | *** | *** |
| W UniFrac | ** | *** | n/s | *** | * | n/s | n/s | *** | *** | ** | n/s | * |
| P-Test | *** | *** | *** | *** | *** | *** | *** | *** | *** | *** | *** | *** |
| Library Compare | ||||||||||||
| Firmicutes | ↑** | ↑*** | ↓*** | ↑*** | ||||||||
| >Clostridiales | ↑*** | ↓*** | ↑*** | |||||||||
| >>Lachnospiraceae | ↑*** | ↓*** | ||||||||||
| >>Ruminococcaceae | ↓** | |||||||||||
| Bacteroidetes | ↓** | ↓*** | ↑*** | ↓*** | ||||||||
| >>>Bacteroides | ↓*** | |||||||||||
| >>>Parabacteroides | ↓** | |||||||||||
| >>>Prevotella | ↑*** | ↑*** | ↓*** | |||||||||
| Actinobacteria | ↑** | |||||||||||
| >>>Collinsella | ↑** | |||||||||||
| Proteobacteria | ↓*** | |||||||||||
| >>>Sutterella | ↓*** | |||||||||||
| Fusobacteria | ↑* | |||||||||||
| >>>Fusobacterium | ↑* | |||||||||||
Key:- *** = P < 0.001, ** = P < 0.01, * = P < 0.05, n/s = P > 0.05. ↑ = Increased in inflamed vs. non-inflamed tissue, ↓ = Decreased in inflamed vs. non-inflamed tissue. Bold = Phylum level classification, > = Order level classification, >> = Family level classification, >>> = Genus level classification.