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. 2011 Jan 12;4:6. doi: 10.1186/1755-8794-4-6

Table 3.

Gene Ontology enrichment analysis for creQTL at q = 0.05.

Gene Ontology Biological Process
Category ID Category Size Category Title qKS
7214 18 gamma-aminobutyric acid signaling pathway < 0.008
7612 21 learning < 0.008
7411 62 axon guidance < 0.008
7156 69 homophilic cell adhesion < 0.008
7417 80 central nervous system development < 0.008
7155 320 cell adhesion < 0.008
45944 203 positive regulation of transcription from RNA polymerase II promoter 0.008
7399 225 nervous system development 0.008
45595 12 regulation of cell differentiation 0.014
48754 19 branching morphogenesis of a tube 0.018
30900 42 forebrain development 0.018
45165 29 cell fate commitment 0.027
43065 69 positive regulation of apoptosis 0.04
7224 16 smoothened signaling pathway 0.043
7420 74 brain development 0.043
30326 35 embryonic limb morphogenesis 0.043
7169 56 transmembrane receptor protein tyrosine kinase signaling pathway 0.043
6813 94 potassium ion transport 0.043
Gene Ontology Cellular Component
Category ID Category Size Category Title qKS
5913 18 cell-cell adherens junction < 0.004
45202 156 synapse < 0.004
30054 231 cell junction < 0.004
14069 49 postsynaptic density 0.004
45211 79 postsynaptic membrane 0.004
30424 83 axon 0.006
781 13 chromosome, telomeric region 0.013
5912 27 adherens junction 0.013
34707 36 chloride channel complex 0.016
5923 40 tight junction 0.016
5886 1504 plasma membrane 0.037
42734 21 presynaptic membrane 0.038
5578 174 proteinaceous extracellular matrix 0.038
Gene Ontology Molecular Function
Category ID Category Size Category Title qKS
8066 11 glutamate receptor activity < 0.008
5216 187 ion channel activity < 0.008
5509 491 calcium ion binding < 0.008
4993 11 serotonin receptor activity < 0.008
4970 12 ionotropic glutamate receptor activity 0.009
5234 12 extracellular-glutamate-gated ion channel activity 0.009
43565 273 sequence-specific DNA binding 0.009
5244 85 voltage-gated ion channel activity 0.016
4890 17 GABA-A receptor activity 0.017
5246 11 calcium channel regulator activity 0.019
31404 49 chloride ion binding 0.023
30594 18 neurotransmitter receptor activity 0.028
30165 32 PDZ domain binding 0.029
5001 13 transmembrane receptor protein tyrosine phosphatase activity 0.029
5267 53 potassium channel activity 0.029
5230 24 extracellular ligand-gated ion channel activity 0.037
5254 48 chloride channel activity 0.041
8146 26 sulfotransferase activity 0.041
16455 11 RNA polymerase II transcription mediator activity 0.042

Results are presented for Biological Process, Cellular Component, and Molecular Function, respectively. Category IDs are presented minus leading zeroes. 'qKS' indicates FDR-adjusted significance of the category.