Table 3.
Significant associations between ADIPOQ SNPs and baseline body weight
| pa/q | pb/q | ||||
|---|---|---|---|---|---|
| rs266729 (N) | CC (219)c | CG, GG (288)d | |||
| All | 85.04 (83.33-86.79) | 87.66 (86.09-89.25) | 0.025/0.024 | 0.020/0.700 | |
| male | 91.36 (88.60-94.21) | 89.69 (87.26-92.19) | 0.385/0.420 | ||
| female | 80.18 (78.16-82.25) | 84.46 (82.63-86.33) | 0.003/0.036 | ||
| rs16861205 (N) | GG (337) | GA (151) | AA (19) | ||
| All | 87.66 (86.20-89.14) | 84.37 (82.33-86.46) | 83.86 (78.36-89.67) | 0.023/0.024 | 0.528/0.684 |
| GG (337) | AA, AG (170) | ||||
| All | 87.65 (86.20-89.13) | 84.31 (82.39-86.26) | 0.006/0.024 | 0.302/0.684 | |
| rs1501299 (N) | GG (234) | GT (220) | TT (53) | ||
| All | 88.09 (86.37-89.84) | 85.36 (83.63-87.13) | 84.16 (80.80-87.66) | 0.032/0.024 | 0.486/0.684 |
| GG (234) | GT, TT (273) | ||||
| All | 88.09 (86.37-89.84) | 85.13 (83.56-86.72) | 0.011/0.024 | 0.407/0.684 | |
| rs3821799 (N) | CC (149) | CT (255) | TT (103) | ||
| All | 89.63 (87.49-91.82) | 85.64 (84.02-87.29) | 83.99 (81.56-86.48) | 0.001/0.024 | 0.187/0.700 |
| CC (149) | CT, TT (358) | ||||
| All | 89.63 (87.49-91.82) | 85.16 (83.78-86.57) | 0.0005/0.024 | 0.072/0.724 | |
| CC, CT (404) | TT (103) | ||||
| All | 87.13 (85.80-88.48) | 84.03 (81.59-86.55) | 0.029/0.024 | 0.861/0.684 | |
| rs6773957 (N) | GG (206) | GA (233) | AA (68) | ||
| All | 88.31 (86.49-90.17) | 85.29 (83.61-87.01) | 84.98 (81.95-88.12) | 0.033/0.024 | 0.200/0.700 |
| GG (206) | AA, AG (301) | ||||
| All | 88.31 (86.50-90.17) | 85.22 (83.72-86.76) | 0.009/0.024 | 0.172/0.684 | |
Data are expressed as retransformed geometric mean (95% CI)
Correction for multiple hypothesis testing was performed with FDR, denoted as q-value.
a adjusted for age and sex
b p for sex-genotype interaction
c Men: N = 74, Women N = 145
d Men: N = 92, Women N = 196