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. Author manuscript; available in PMC: 2011 Dec 21.
Published in final edited form as: Biochemistry. 2010 Nov 23;49(50):10666–10673. doi: 10.1021/bi1013485

FIGURE 4.

FIGURE 4

Uptake of ribonucleases by chemical- or enzyme-treated mammalian cells. Labeled DRNG RNase A and ONC were incubated for 1 and 3 h, respectively, with CHO-K1 cells that had been treated with d-threo-PPMP, V8 protease, or neuraminidase. Total cell fluorescence was measured by flow cytometry. Values of fluorescence intensity are the mean (±SE) for 20,000 cells from ≥6 cell populations.