Table 2.
Values of IC50 (µM) for cell proliferation in the presence of ribonucleasesa
ribonuclease | |||
---|---|---|---|
Cell line | |||
DRNG RNase A | KDRNG RNase A | ONC | |
CHO-K1 | 18.5 ± 0.1 | 20.1 ± 0.1 | 2.2 ± 0.1 |
CHO-745 | 27.1 ± 0.1 | 39.8 ± 0.03 | 0.6 ± 0.3 |
Pro 5 | 4.63 ± 0.09 | 8.79 ± 0.03 | 0.4 ± 0.1 |
Lec 2 | 6.7 ± 0.1 | 14.44 ± 0.04 | 0.6 ± 0.2 |
Values of IC50 (±SE) are for incorporation of [methyl-3H]thymidine into the DNA of cells treated with a ribonuclease.