Table 2.
Selective DOT county | Universal DOT county | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
(n = 1207) | (n = 514) | Crude | Adjusted1 | |||||||
Isolate characteristic | No. | (%) | No. | (%) | OR | (95% CI) | p-value | OR | (95% CI) | p-value |
EMB/INH/RIF resistant2 | ||||||||||
No | 1108 | (92) | 489 | (95) | 1.0 | 0.03 | 1.0 | 0.049 | ||
Yes | 95 | (8) | 25 | (5) | 1.7 | (1.1, 2.6) | 1.6 | (1.1, 2.6) | ||
Unknown | 4 | |||||||||
Belongs to a resistant cluster3 | ||||||||||
No | 927 | (77) | 454 | (88) | 1.0 | <0.0001 | 1.0 | <0.0001 | ||
Yes | 280 | (23) | 60 | (12) | 2.3 | (1.7, 3.1) | 2.1 | (1.6, 2.9) | ||
Belongs to a two-isolate resistant cluster4 | ||||||||||
No | 1024 | (85) | 495 | (96) | 1.0 | <0.0001 | 1.0 | <0.0001 | ||
Yes | 183 | (15) | 19 | (4) | 4.7 | (2.9, 7.6) | 4.3 | (2.6, 7.0) |
1Adjusted for age, race, and HIV status.
2Resistant to EMB, INH, and/or RIF.
3Genotype-clustered with at least one isolate in cluster resistant to EMB, INH, and/or RIF.
4Genotype-clustered with at least two of the EMB-, INH- and/or RIF-resistant isolates having the same EMB-INH-RIF resistance pattern.