Table 3.
Replication and transmission study of recombinant virus 2H7N2:6WF10att and 2mH7N2:6WF10att in quail
| Virus | Group | # of positive tracheal swab/total # post-inoculation (log10TCID50/ml ± SD) at peak viral shedding | # of seroconverted/total # (Average HI titer at 14 dpi) | ||||
|---|---|---|---|---|---|---|---|
| 1 dpi | 3 dpi | 5dpi | 7 dpi | 9 dpi | |||
| 2H7N2:6WF10att | Inoculated | 6/6 (2.9 ± 0.4) | 6/6* | 3/3 | 0/3 | 0/3 | 3/3 (133) |
| Contact | NA | 3/3 (1.6 ± 1.4) | 3/3 | 2/3 | 0/3 | 3/3 (47) | |
| 2mH7N2:6WF10att | Inoculated | 6/6 (<0.7) | 6/6* | 1/3 | 1/3 | 0/3 | 3/3 (87) |
| Contact | NA | 0/3 | 0/3 | 2/3 (<0.7) | 0/3 | 2/3 (10) | |
* 3 quail from each inoculated group were sacrificed at 3 dpi to determine virus load in the lungs.