Table 4.
Association between TSLP SNP rs1837253 minor allele T* and allergic rhinitis in Costa Rica, CAMP, and BAMSE
| Costa Rica | CAMP | BAMSE | Combined | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects | T:U† | OR | P value | T:U | OR | P value | OR | P value | Fisher's P value |
| All children | 104:122 | 0.85 | 0.18 | 50:81 | 0.62 | 0.003 | 0.72 | 0.089 | 0.003 |
| Boys | 59:93 | 0.63 | 0.004 | 32:55 | 0.58 | 0.007 | 0.56 | 0.04 | 1.2 × 10-4 |
| Girls^ | 45:29 | 1.55 | 0.08 | 18:26 | 0.69 | 0.11 | 1.02 | 0.48 | |
*Allele frequency 0.24 in Costa Rica, 0.21 in CAMP, 0.27 in BAMSE
†T:U = ratio of transmitted to untransmitted alleles
^Fisher's combined P value not calculated because direction of effect inconsistent across females in these cohort.