Table 1.
Surface marker expression* | HIV(+) ART-naïve (n = 199) | HIV(+) ART ≥ 24 weeks§ (n = 57) | HIV (−) (n = 30) | pa | pb | pc |
---|---|---|---|---|---|---|
CD8− | ||||||
CD3+CD8− CD38+ HLADR+ | 13 (10–17) | 10 (6–14) | 5 (4–6) | 0.005 | < 0.001 | < 0.001 |
CD3+CD8− CD38+ HLADR− | 76 (68–81) | 76 (68–80) | 78 (72–80) | 0.80 | 0.32 | 0.25 |
CD3+CD8− CD38− HLADR+ | 2 (1–2) | 2 (1–2) | 2 (1–2) | 0.25 | 0.25 | 0.94 |
CD8 | ||||||
CD3+CD8+ CD38+ HLADR+ | 45 (34–54) | 30 (21–40) | 18 (13–21) | < 0.001 | < 0.001 | < 0.001 |
CD3+CD8+ CD38+ HLADR− | 50 (40–58) | 62 (47–66) | 66 (62–72) | < 0.001 | < 0.001 | 0.004 |
CD3+CD8+ CD38− HLADR+ | 1 (1–3) | 2 (1–4) | 3 (2–6) | 0.003 | < 0.001 | 0.08 |
Percent of cells expressing, median (25th–75th%’ile);
median: 37.9 week (32.0–60.1).
p: p-value for Wilcoxon two-sample test;
HIV(+) ART-naïve vs. ART ≥ 24 weeks;
HIV(+) ART-naïve vs. HIV (−);
HIV(+) ART ≥ 24 weeks vs. HIV (−).