Table 6.
Summary of the evaluation regarding size, polarity, secondary structure, solvent accessibility of the predicted sites in comparison to the catalytic ones, as well as TPR, FPR and the overall performance of the methods based on MCC, F-measure and the ROC analysis
| Method | Size | Polarity | Secondary structure | Solvent accessibility | TPR | FPR | Performance |
|---|---|---|---|---|---|---|---|
| CASTp | ** | * | *** | * | ** | ** | ** |
| ConSurf | * | ** | * | ** | *** | * | ** |
| FOD | ** | * | * | ** | ** | ** | *** |
| PASS | ** | * | ** | * | ** | ** | * |
| Pocket-Finder | ** | * | ** | * | ** | ** | ** |
| Q-SiteFinder | ** | ** | *** | * | ** | ** | ** |
| SuMo | *** | * | *** | *** | ** | ** | *** |
| WebFEATURE | ** | ** | ** | ** | * | *** | * |
The more accurate results are denoted by the higher number of asterisks