Figure 4.
A wild-type amn+ gene whose expression is driven by amn28A and amnX8 GAL4 activities rescues the thermal nociception defect in amn mutants. Nociception assays were performed for animals trans-heterozygous for amn28A and amnX8, with or without the UAS-amn+ transgene. Latencies of the responses to a noxious heat stimulus are shown as box plots, for larvae (A) and adult flies (B). The amn28A/amnX8; UAS-amn+/+ flies displayed response latencies that were reduced in comparison to those of amn28A/amnX8 flies. ***P < 0.001 (Mann-Whitney Rank Sum Test).