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. Author manuscript; available in PMC: 2012 Jan 12.
Published in final edited form as: Structure. 2011 Jan 12;19(1):37–44. doi: 10.1016/j.str.2010.11.008

Figure 1. Comparison of the two CAR ligands used in this study.

Figure 1

(A) The chemical structures of CAR and TCPOBOP are shown. (B) TCPOBOP is a more potent agonist in cell-based reporter gene assays using the βRE response element. The data is shown in relative luciferase units (RLU). (C) TCPOBOP promotes higher affinity for coactivator than meclizine in ITC experiments.