Figure 2.

Dynamics of viral infection for different initial conditions. (a) The starting condition of the simulation is a single viral genome; this results in the virus being silenced. (b) The starting condition is that 10 viral genomes infect the cell; this high multiplicity of infection results in exponential viral replication after a period of latency of 1 day required to reach a threshold level of RdRps. This successful infection happens even in the absence of a VSR. The parameters values are those shown in table 1.