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Illustrative example of a network with two modules. Each circle represents a module, i.e. a group of biochemical species. The network species are grouped into three non-overlapping sets A, B and D as shown, in such a way that At↮Dt Bt —i.e. the trajectories (up to any time t) of A and B are independent given the trajectory of D. Hence At and Bt contain no mutual information given Dt, all information transfer between the two modules being conveyed via Dt.
