Table. Risk factors for the Beijing genotype of Mycobacterium tuberculosis, the Netherlands, 1993–2000.
Risk factor | Beijing genotype | Total | (%) | Odds ratio |
|
---|---|---|---|---|---|
Crude | Adjustedb (95% confidence intervals) | ||||
Y of diagnosis
| |||||
1993 |
23 |
669 |
3 |
1.09 |
1.08 (1.03 to 1.13) |
1994 |
41 |
941 |
4 |
(per year) |
|
1995 |
56 |
863 |
6 |
|
|
1996 |
50 |
946 |
5 |
|
|
1997 |
64 |
872 |
7 |
|
|
1998 |
58 |
804 |
7 |
|
|
1999 |
74 |
879 |
8 |
|
|
2000 |
49 |
855 |
6 |
|
|
Sex
| |||||
Male |
254 |
4,135 |
6 |
1 |
|
Female |
161 |
2,694 |
6 |
0.97 |
|
Age group
| |||||
<25 |
120 |
1,522 |
8 |
1 |
1 |
25–34 |
123 |
1,925 |
6 |
0.80 |
0.69 (0.53 to 0.91) |
35–44 |
64 |
1,080 |
6 |
0.74 |
0.60 (0.43 to 0.83) |
45–54 |
23 |
614 |
4 |
0.45 |
0.36 (0.23 to 0.57) |
55–64 |
24 |
493 |
5 |
0.60 |
0.55 (0.35 to 0.88) |
65–74 |
40 |
517 |
8 |
0.98 |
0.78 (0.52 to 1.15) |
75+ |
21 |
678 |
3 |
0.37 |
0.30 (0.18 to 0.50) |
Nationality
| |||||
Netherlands |
160 |
2,825 |
6 |
1 |
1 |
Europe (central and eastern) |
20 |
231 |
9 |
1.58 |
1.27 (0.77 to 2.09) |
Turkey |
3 |
339 |
1 |
0.15 |
0.12 (0.04 to 0.38) |
Morocco |
19 |
650 |
3 |
0.50 |
0.41 (0.25 to 0.68) |
Somalia |
21 |
957 |
2 |
0.37 |
0.27 (0.17 to 0.44) |
Africa (other) |
28 |
594 |
5 |
0.82 |
0.63 (0.41 to 0.96) |
Asia |
140 |
786 |
18 |
3.61 |
3.01 (2.32 to 3.91) |
Other |
19 |
345 |
6 |
0.97 |
0.86 (0.53 to 1.42) |
Unknown |
5 |
102 |
5 |
0.86 |
0.73 (0.29 to 1.84) |
RFLP clusteringa
| |||||
No |
212 |
3,227 |
7 |
1 |
|
Yes, first case |
57 |
1,052 |
5 |
0.81 |
|
Yes, later case |
146 |
2,550 |
6 |
0.86 |
|
Localization
| |||||
Pulmonary |
268 |
4,064 |
7 |
1 |
|
Extrapulmonary |
113 |
2,122 |
5 |
0.80 |
|
Pulmonary and extrapulmonary |
34 |
643 |
5 |
0.79 |
|
Residing in Netherlands
| |||||
<6 months |
46 |
641 |
7 |
1 |
|
6–11 mo |
12 |
301 |
4 |
0.54 |
|
12–23 mo |
28 |
358 |
8 |
1.10 |
|
2–4 y |
53 |
767 |
7 |
0.96 |
|
>5 y |
122 |
1,710 |
7 |
0.99 |
|
Born in Netherlands |
117 |
2,437 |
5 |
0.65 |
|
No information |
37 |
615 |
6 |
0.83 |
|
Drug resistance
| |||||
Susceptible |
332 |
5,910 |
6 |
1 |
|
H only |
11 |
227 |
5 |
0.86 |
|
S only |
34 |
358 |
9 |
1.76 |
|
Other patterns |
26 |
221 |
12 |
2.24 |
|
Multidrug-resistant |
9 |
53 |
17 |
3.44 |
|
Unknown |
3 |
60 |
5 |
0.88 |
|
Multidrug resistance
| |||||
Yes |
9 |
53 |
17 |
3.21 |
2.64 (1.22 to 5.74) |
No |
406 |
6,776 |
6 |
1 |
1 |
HIV infection
| |||||
Yes |
14 |
294 |
5 |
0.76 |
|
No | 401 | 6,535 | 6 | 1 |
aRFLP, restriction fragment length polymorphism.
bAdjusted for year of diagnosis, age, nationality, and multidrug resistance