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. 2010 Dec 6;20(5):917–926. doi: 10.1093/hmg/ddq530

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© The Author 2010. Published by Oxford University Press

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Quantitative analysis of Esrrg^−/− mouse embryonic kidneys using OPT imaging. Digital sections from OPT scans of paired 17 dpc embryonic kidneys dissected from littermates of Esrrg^+/−/Esrrg^+/− matings. Eight kidneys from four wild-type embryos (WT), six kidneys from three Esrrg^+/− embryos (HET) and six kidneys from three Esrrg^−/− embryos (KO) are shown in midline saggital plane defined by analysis of the 3D digital image. The graph shows the range (box), mean (solid line) and error bars (dotted lined) for each genotype group of the luminal volume (right-hand graph) and ratio of lumen to kidney parenchyma for whole kidneys.