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Proposed Steps in the TMC biosynthetic pathway. Abbreviations: KS – ketosynthase, AT – acyltransferase, ACP – acyl carrier protein, DH – dehydratase, KR – ketoreductase, ER – enoylreductase, TE – thioesterase. Domains predicted to be inactive are marked with an “X”. Domains that are active but not utilized are indicated with an “*”. The ordering of post-PKS tailoring reactions is unknown.
