Table 3.
Clinical characteristics of female PAD patients according to HDL-C status (HDL-C < 50 mg/dL versus HDL-C ≥ 50 mg/dL). Data are summarized as the median (25th–75th percentile) or count (%).
| HDL-C < 50 mg/dL (n=43) | HDL-C ≥ 50 mg/dL (n=26) | p- value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Median | P25 | P75 | n | Median | P25 | P75 | ||
| Age, years | 43 | 63.0 | 58.0 | 71.0 | 26 | 67.5 | 58.0 | 73.0 | 0.25 |
| Weight, kg | 43 | 82.1 | 66.3 | 89.2 | 26 | 75.3 | 61.1 | 92.7 | 0.45 |
| BMI, kg/m2 | 43 | 31.0 | 26.5 | 34.7 | 26 | 27.3 | 23.2 | 34.3 | 0.19 |
| ABI at rest | 43 | 0.7 | 0.5 | 0.9 | 26 | 0.8 | 0.6 | 0.9 | 0.19 |
| Duration of IC, years | 40 | 3.5 | 1.0 | 7.5 | 24 | 5.0 | 3.5 | 10.0 | 0.081 |
| WIQ distance score, % | 42 | 13.7 | 3.1 | 38.1 | 25 | 25.1 | 3.6 | 39.6 | 0.58 |
| WIQ speed score, % | 42 | 15.2 | 7.6 | 35.8 | 25 | 25.0 | 10.9 | 39.1 | 0.36 |
| WIQ stair climbing score, % | 42 | 12.5 | 4.1 | 33.0 | 25 | 12.5 | 0.0 | 50.0 | 0.65 |
| WIQ total score | 42 | 50.0 | 25.0 | 75.0 | 26 | 37.5 | 25.0 | 75.0 | 0.89 |
| n | Count (%) | n | Count (%) | p-value | |||||
| Race, % Caucasian | 43 | 19 (44%) | 26 | 13 (50%) | 0.64 | ||||
| Coronary Artery Disease, % | 43 | 18 (42%) | 26 | 4 (15%) | 0.022 | ||||
| Diabetes, % | 43 | 18 (42%) | 26 | 6 (23%) | 0.11 | ||||
| Hypertension, % | 42 | 31 (74%) | 26 | 20 (77%) | 0.77 | ||||
| Current Smoking, % | 43 | 18 (42%) | 25 | 9 (36%) | 0.63 | ||||
| Obesity, % | 43 | 23 (53%) | 26 | 10 (38%) | 0.23 | ||||
| Dyslipidemia, % | 43 | 43 (100%) | 26 | 18 (69%) | ------------ | ||||
| On hormone replacement therapy, % | 43 | 6 (14%) | 26 | 6 (23%) | 0.35 | ||||
BMI, body mass index; ABI, ankle-brachial index; IC, intermittent claudication; WIQ, walking impairment questionnaire. Obesity was defined as having a BMI greater than 30 kg/m2