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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Cancer Res. 2010 Dec 28;71(3):964–975. doi: 10.1158/0008-5472.CAN-10-3172

Figure 1. Sirt1 Deletion Alters Androgen-Responsive Tissue Development.

Figure 1

(A) RT-PCR using ventrodorsolateral prostate RNA from Sirt1+/+ and Sirt1-/- mice. (B) Mean body length, (C) mass, and (D) select tissue weights normalized to total mass (see also Fig. S1A). (E) Hematoxylin and Eosin (H&E) staining of prostate glands from Sirt1+/+and Sirt1-/- mice (see also Fid. S1B). (F) Ki67 staining of Sirt1+/+ and Sirt1-/- prostates. All data are mean ± standard error of the mean (SEM) and represent n=5/genotype. P values were determined by student's t-test (*P<0.05, **P<0.01, ***P<0.001, † denotes no statistical significance).