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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Cancer Res. 2010 Dec 28;71(3):964–975. doi: 10.1158/0008-5472.CAN-10-3172

Figure 6. Chemical Inhibition of SIRT1 Abolishes Autophagy in Prostate Cancer Cells.

Figure 6

(A,B) LNCaP-GFP and LNCaP-LC3-GFP cells cultured in various media conditions in the presence and absence of Sirtinol (30μM) and analyzed by confocal microscopy for LC3 punctae. Statistical significance of triplicate experiments was measured by Mann Whitney U test (***P<0.001, † denotes no statistical significance).