Table 2.
Levels of mI, mIG, Glu and Gln as quantified by QUEST and LCModel (mean±SD). Statistics were evaluated using Tukey’s honestly significant difference tests.
| Methods | Metabolite | Group | Levels | Population | G3 | G4 |
|---|---|---|---|---|---|---|
| QUEST | mI | Normal | 2.8±0.9 | N=20 | ||
| G3 | 3.8±1.2 | N=5 | ||||
| G4 | 2.8±1.7 | N=8 | ||||
| mIG | Normal | 3.6±1.1 | N=20 | |||
| G3 | 5.1±1.8 | N=5 | ||||
| G4 | 3.3±1.6 | N=8 | ||||
| Glu | Normal | 2.3±0.5 | N=14 | P<0.05 | ||
| G3 | 3.1±0.8 | N=4 | P<0.05 | |||
| G4 | 2.1±0.5 | N=4 | P<0.05 | |||
| Gln | Normal | 2.5±0.9 | N=19 | |||
| G3 | 2.7±0.1 | N=2 | ||||
| G4 | 2.3±0.7 | N=9 | ||||
| LCModel | mI | Normal | 5.9±1.5 | N=14 | P<0.005 | |
| G3 | 10.4±2.4 | N=4 | P<0.05 | |||
| G4 | 6.4±2.7 | N=5 | P<0.05 | |||
| Glu | Normal | 6.3±1.9 | N=14 | n/a | ||
| G3 | 8.4 | N=1 | ||||
| G4 | 5.4±1.5 | N=3 | n/a | |||
| Gln | Normal | 2.2±0.3 | N=3 | |||
| G3 | 2.4±0.6 | N=4 | P=0.05 | |||
| G4 | 1.5±0.5 | N=5 | P=0.05 |
N=number of patients