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. Author manuscript; available in PMC: 2011 Dec 27.
Published in final edited form as: Transplantation. 2010 Dec 27;90(12):1381–1387. doi: 10.1097/TP.0b013e3181ffbadd

Figure 5. Receiver-Operating-Characteristic Curves of mRNA Levels for Predicting Graft Loss.

Figure 5

The fraction of true positive results (sensitivity) and false positive results (1-specificity) for levels of mRNA, each normalized for 18S rRNA, are displayed as predictors of graft loss within 6 months of biopsy proven acute rejection. The calculated area under the curve was 0.74 (95 percent confidence interval, 0.51 to 0.97) for OX40 mRNA levels (P=0.04, Panel A), 0.68 (95 percent confidence interval, 0.44 to 0.92) for OX40L mRNA levels (P=0.14, Panel B), 0.75 (95 percent confidence interval, 0.52 to 0.98) for the best linear combination of levels of mRNA for OX40 and OX40L (P=0.04, Panel C). A value of 0.5 is considered no better than predicted by chance and a value of 1.0 is considered a perfect indicator.