Table 2.
Functional categories significantly over-represented in the up- or down-modulated genes at 35 days of age by the effects of in utero exposure to low dose of BBP
| Function | GO | p-value | |
|---|---|---|---|
| Up-modulated | signal transduction | GO:0007165 | 6.86E-04 |
| GO:0007242 | |||
| cell communication | GO:0007154 | 9.62E-04 | |
| metabolic process | GO:0008152 | 2.64E-03 | |
| GO:0044238 | |||
| apoptosis | GO:0006915 | 3.68E-03 | |
| transport | GO:0006810 | 6.42E-03 | |
| cellular process | GO:0009987 | 7.55E-03 | |
| other | GO:0008015 | 1.30E-03 | |
| GO:0006936 | 1.34E-03 | ||
| Down-modulated | primary metabolic process | GO:0044238 | 2.00E-06 |
| GO:0008152, GO:0006139, GO:0005975, GO:0019538 |
|||
| cellular process | GO:0009987 | 3.63E-05 | |
| transport | GO:0006810 | 1.44E-04 | |
| GO:0006886, GO:0015031, GO:0006897, GO:0016192 |
|||
| cell cycle | GO:0007049 | 1.84E-03 | |
| GO:0007067 | |||
| immune system process | GO:0002376 | 2.64E-03 | |
| cell-matrix adhesion | GO:0007160 | 3.05E-03 | |
| apoptosis | GO:0006915 | 4.63E-03 | |
| other | GO:0007269 | 5.80E-03 | |
| GO:0007059 | 6.14E-03 | ||
GO, Gene Ontology class.