Table 3.
Functional categories significantly over-represented in the up- or down-modulated genes at 35 days of age by the effects of in utero exposure to high dose of BBP
| Function | GO | p-value | |
|---|---|---|---|
| Up-modulated | metabolic process | GO:0008152, | 6.71E-14 |
| GO:0044238, GO:0006629, GO:0005975, GO:0019538, GO:0006800, GO:0006807, GO:0006519, GO:0006732, GO:0006091, GO:0006766, GO:0006790, GO:0022904 |
|||
| cell communication | GO:0007154 | 1.04E-09 | |
| signaling | GO:0007165 | 2.78E-09 | |
| GO:0007242, GO:0007267, GO:0007166 | |||
| transport | GO:0006810 | 5.14E-09 | |
| GO:0006886, GO:0015031, GO:0006897, GO:0006869, GO:0016192, GO:0006811, GO:0051180, GO:0008643, GO:0006812 |
|||
| immune system process | GO:0002376 | 4.12E-08 | |
| cellular process | GO:0009987 | 1.73E-07 | |
| cell adhesion | GO:0007155 | 4.50E-07 | |
| GO:0007160, GO:0016337 | |||
| system process | GO:0003008 | 8.59E-07 | |
| GO:0050877, GO:0008015, GO:0007601, GO:0007268 |
|||
| response to stimulus | GO:0050896 | 3.96E-05 | |
| GO:0009605, GO:0006950, GO:0009636 | |||
| homeostatic process | GO:0042592 | 1.22E-04 | |
| GO:0007596,GO:0001678 | |||
| developmental process | GO:0032502 | 5.03E-04 | |
| GO:0009948, GO:0007399, GO:0048731, GO:0007398 |
|||
| apoptosis | GO:0006915 | 1.91E-03 | |
| Down-modulated | cellular process | GO:0009987 | 5.88E-18 |
| metabolic process | GO:0008152 | 1.14E-17 | |
| GO:0044238, GO:0006139, GO:0019538, GO:0005975, GO:0006091, GO:0022904 |
|||
| cell cycle | GO:0007049 | 6.21E-13 | |
| GO:0007067 | |||
| cell communication | GO:0007154 | 2.02E-09 | |
| GO:0007269 | |||
| intracellular signaling cascade | GO:0007242 | 1.39E-08 | |
| GO:0007165, GO:0007267, GO:0007166 | |||
| cell motion | GO:0006928 | 8.25E-07 | |
| transport | GO:0006810 | 5.83E-06 | |
| GO:0008643, GO:0006886, GO:0015031, GO:0016192 |
|||
| cellular component organization | GO:0016043 | 2.56E-05 | |
| GO:0006325, GO:0006996 | |||
| apoptosis | GO:0006915 | 9.20E-05 | |
| GO:0043066 | |||
| immune system process | GO:0002376 | 1.07E-04 | |
| developmental process | GO:0032502 | 5.31E-04 | |
| GO:0048731, GO:0007399, GO:0007398 | |||
| cell adhesion | GO:0007155 | 5.75E-04 | |
| GO:0016337, GO:0007160 | |||
| response to stimulus | GO:0050896 | 2.18E-03 | |
| GO:0006950 | |||
| system process | GO:0003008 | 2.45E-03 | |
| GO:0050877, GO:0007601, GO:0007268 | |||
| Other | GO:0000910 | 2.32E-03 | |
| GO:0007276 | 7.53E-03 | ||
GO, Gene Ontology class.