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. 2011 Jan 18;108(5):2094–2099. doi: 10.1073/pnas.1011508108

Fig. 5.

Fig. 5.

(A) Time-dependent changes in food intake (g/h per mouse) in WT (n = 28–32), gust−/− (n = 24–32) and GHS-R−/− mice (n = 12–14) after gavage of water or T2R-agonists. (B) Effect of intragastric gavage of water (open bars), the bitter mixture or the individual T2R-agonists (filled bars) on gastric emptying in WT mice (n = 6–8). (C) Effect of water (control), the bitter mixture and the individual T2R-agonists on 4-h food intake in WT mice (n = 16). (D) Correlation between gastric emptying and 4-h food intake (R2 = 0.94, P < 0.01). **P < 0.01, ***P < 0.001 vs. control.