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(A) The effect of oral administration of T2R-agonists on gastric emptying in WT (n = 10), gust−/− (n = 12) and GHS-R−/− (n = 8) mice. (B and C) Effect of the CCK antagonist (devazepide) and the GLP-1 antagonist [exendin(9-39)], administered i.p. 15 min before gavage of T2R-agonists, on gastric emptying in WT mice. ***P < 0.001 vs. control; #P < 0.05 WT vs. gust−/− or GHS-R−/−.
