Fig. 2.

L-II RNA activates NF-κB. (A) Activation of NF-κB by the L-II mut. The L-II mutant contains a stop codon in place of the start codon of L-II. A reporter gene assay was performed as described in Fig.1A. (B) Activation of NF-κB by L-II RNA is independent of AKT1. A dual-luciferase experiment was performed using AKT1 inhibitor (Inh) (Left) or AKT1 DN (Right), along with L, L-II, L-II mut, or L-I-II plasmids as described in Fig. 1B. All transfections were carried out in replicates of four. Error bars indicate SD.