Figure 6. Model predictions of threshold ribavirin exposure and requisite RBC production.
A, Prediction of
as a function of
. The arrow indicates the threshold
above which
<10 g/dL. B, Predictions of the RBC production rate during therapy (black) and the production rate required to maintain
of 10 g/dL (pink) and 12 g/dL (blue) as functions of
. The arrows indicate the desired production rates when
. Parameter values employed are mentioned in Table 1.
