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. 2011 Feb 3;7(2):e1002002. doi: 10.1371/journal.pcbi.1002002

Figure 5. Single-exponential kinetics of unbinding.

Figure 5

The plot shows the cumulative distribution Inline graphic of the unbinding times; Inline graphic, where Inline graphic is the probability distribution of the unbinding time. An unbinding event is defined by a separation between the centers of mass of the FKBP active site and the ligand larger than 15 Å. The stars represent the 40 unbinding events observed in the 50 MD runs of BUT. The single-exponential fit (solid line) yields Inline graphic ns.