FIG. 7.

Induction of liver acute phase response gene expression in STAT3SA/− mice. Littermate STAT3+/+ and STAT3SA/− mice were injected with turpentine subcutaneously or recombinant IL-6 intraperitoneally. After 12 h of turpentine injection or 6 h of IL-6 injection, liver total RNA was prepared from each animal and analyzed by RT-PCR. As negative controls, mice were either left untreated or injected with sterile pyrogen-free saline. SAA, serum amyloids A; SAP, serum amyloids P; FB, fibrinogen; HP, haptoglobin; HPX, hemopexin; AGP, α1-acid glycoprotein.