Table 2. Genetic distribution of recipient/donor SDF1 and CXCR4 Single Nucleotide Polymorphisms.
| Donor | P valuefor trend | Recipient | P valuefor trend | ||||||
| Genotype | BPAR (−), n (%) | BPAR (+), n (%) | OR (95% CI) | BPAR (−), n (%) | BPAR (+), n (%) | OR (95% CI) | |||
| SDF-1 rs1801157 | GG | 138 (54.8) | 43 (75.4) | 1.00 (reference) | 0.003 | 144 (53.7) | 33 (55.9) | 1.00 (reference) | 0.460 |
| GA | 89 (35.3) | 13 (22.8) | 0.47 (0.24–0.92) | 103 (38.4) | 24 (40.7) | 1.02 (0.57–1.82) | |||
| AA | 25 (9.9) | 1 (1.8) | 0.13 (0.02–0.98) | 21 (7.8) | 2 (3.4) | 0.42 (0.09–1.86) | |||
| GA+AA vs. GG | 114 (45.2) | 14 (24.6) | 0.39 (0.21–0.76) | 0.005 | 124 (46.3) | 26 (44.1) | 0.92 (0.52–1.61) | 0.759 | |
| Total | 252 (100) | 57(100) | 268(100) | 59 (100) | |||||
| CXCR4 rs2228014 | CC | 201 (58.0) | 45 (80.4) | 1.00 (reference) | 0.975 | 201 (78.8) | 45 (81.8) | 1.00 (reference) | 0.463 |
| CT | 43 (32.4) | 11 (19.6) | 1.14 (0.55–2.39) | 49 (19.2) | 10 (18.2) | 0.91(0.43–1.94) | |||
| TT | 3 (9.6) | 0 (0.0) | NA | 5 (2.0) | 0 (0.0) | NA | |||
| CT+TT vs. CC | 46 (42.0) | 11 (19.6) | 1.07 (0.51–2.22) | 0.860 | 54 (21.2) | 10 (18.2) | 0.83 (0.39–1.75) | 0.619 | |
| Total | 247 (100) | 56 (100) | 255 (100) | 55(100) | |||||
BPAR, biopsy-proven acute rejection; OR, odds ratio; CI, confidence interval; N/A, modeling not completed because SNP frequency = 0% in BPAR (−) and/or BPAR (+).