Table 3. The independent risk factor to the incidence of acute rejection analyzed by multivariate logistic regression.
Donor | Recipient | |||||
OR | 95% CI | P value | OR | 95% CI | P value | |
SDF-1 rs1801157 | GA+AA vs. GG | GA+AA vs. GG | ||||
Model 1a | 0.40 | 0.21–0.78 | 0.007 | 0.88 | 0.50–1.57 | 0.666 |
Model 2b | 0.40 | 0.21–0.77 | 0.006 | 0.88 | 0.50–1.57 | 0.674 |
Model 3c | 0.39 | 0.20–0.76 | 0.006 | 0.88 | 0.49–1.57 | 0.657 |
CXCR4 rs2228014 | CT+TT vs. CC | CT+TT vs. CC | ||||
Model 1a | 1.12 | 0.53–2.34 | 0.772 | 0.90 | 0.42–1.93 | 0.793 |
Model 2b | 1.11 | 0.53–2.34 | 0.778 | 0.92 | 0.43–1.98 | 0.831 |
Model 3c | 1.11 | 0.53–2.34 | 0.785 | 0.92 | 0.43–1.97 | 0.819 |
a, adjusted for recipient's age and recipient's gender;
b, adjusted for recipient's age, recipient's gender, number of HLA mismatching, donor type;
c, adjusted for recipient's age, recipient's gender, number of HLA mismatching, donor type, number of transplantation, hypertension, and diabetes mellitus.
OR, odds ratio; CI, confidence interval.