Table 2. Parameter configurations used in our simulation study.
Genetic effecta | ||||
Epistatic model | D' | SNP6 | SNP10 | SNP6×SNP10 |
0.9∼1.0 | 0.020 | 0.010 | 0.000 | |
0.8∼0.9 | 0.018 | 0.008 | 0.004 | |
0.7∼0.8 | 0.016 | 0.006 | 0.008 | |
0.6∼0.7 | 0.014 | 0.004 | 0.012 |
denote the phenotypic variance explained by additive effects of causal SNP 6 and SNP 10 as well as interactive effect between SNP 6 and SNP 10, respectively.
denote the phenotypic variance explained by additive effect of causal SNP 8.
the basic parameter configuration is highlighted in bold. Each possible parameter setting can be obtained by replacing one entry of the basic parameter configuration with a different entry of corresponding parameter.