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. 2011 Feb 3;342:d199. doi: 10.1136/bmj.d199

Table 11.

 Intensive care outcomes in phase two of Safer Patients Initiative (SPI2). Median and interquartile ranges for control and intervention hospitals, before and after intervention period*

Intensive and critical care outcomes* Control hospitals SPI2 hospitals Difference in difference
Before After Before After Change (99% CI)† P value
Adjusted mortality ratio 1.14 (0.99-1.32) 1.24 (1.02-1.33) 1.04 (0.90-1.15) 0.97 (0.90-1.15) 0.09 (−0.11 to 0.29) 0.25
Mean LOS (hours) 144 (117-174) 147 (126-185) 102 (82-130) 103 (81-137) 5.86 (−22.78 to 34.50) 0.60
Mean APACHE II score 20.4 (17.7-22.6) 19.0 (17.1-20.8) 21.1 (19.1-23.0) 20.3 (17.8-21.8) −0.83 (−3.63 to 1.98) 0.459
Mean ICNARC score 22.3 (19.5-26.3) 20.7 (18.0-23.5) 22.6 (21.2-25.3) 22.2 (19.7-25.1) −2.26 (−6.39 to 1.87) 0.16

LOS=length of stay; APACHE=acute physiological and chronic health evaluation; ICNARC=Intensive Care National Audit and Research Centre.

*Before period is October 2006 to March 2007 and after period is October 2008 to March 2009.

†Change <1 favours SPI2.