Table 5.
Control hospitals | SPI2 hospitals | OR (99% CI)†, P value | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Epoch 1 (n=120) | Epoch 2 (n=123) | Epoch 3* (n=112) | Epoch 1 (n=116) | Epoch 2 (n=117) | Epoch 3* (n=114) | Changes in controls | Effect of SPI2 | |||
On admission | ||||||||||
Temperature | 97 (2) | 99 (1) | 99 (1) | 99 (1) | 99 (1) | 97 (2) | 0.7 (0.02 to 24.0), 0.823 | 0.1 (0.002 to 4.1), 0.108 | ||
Respiratory rate | 96 (2) | 99 (1) | 100 | 97 (2) | 98 (1) | 100 | NA | NA | ||
Cyanosis/oxygen saturation | 98 (1) | 98 (1) | 100 | 99 (1) | 99 (1) | 100 | NA | NA | ||
Confusion/mental state | 53 (5) | 72 (4) | 74 (4.2) | 63 (5) | 57 (5) | 81 (4) | 1.8 (0.8 to 3.7), 0.045 | 1.7 (0.6 to 4.5), 0.187 | ||
Pulse | 98 (1) | 99 (1) | 100 | 99 (1) | 99 (1) | 100 | NA | NA | ||
Blood pressure | 98 (1) | 99 (1) | 100 | 99 (1) | 99 (1) | 100 | NA | NA | ||
At 6 hours | ||||||||||
Temperature | 62 (5) | 70 (4) | 70 (4) | 63 (5) | 78 (4) | 68 (4) | 1.4 (0.7 to 2.8), 0.239 | 0.8 (0.3 to 1.9), 0.457 | ||
Respiratory rate | 41 (5) | 69 (4) | 72 (4) | 47 (5) | 76 (4) | 78 (4) | 2.1 (1.0 to 4.3), 0.010 | 1.0 (0.4 to 2.8), 0.907 | ||
Pulses | 69 (4) | 73 (4) | 75 (4) | 65 (5) | 81 (4) | 80 (4) | 1.3 (0.6 to 2.8), 0.327 | 1.2 (0.4 to 3.3), 0.662 | ||
Oxygen saturation | 62 (5) | 72 (4) | 74 (4) | 61 (5) | 79 (4) | 80 (4) | 1.4 (0.7 to 3.0), 0.223 | 1.2 (0.4 to 3.1), 0.703 | ||
At 12 hours | ||||||||||
Temperature | 58 (5) | 71 (4) | 69 (4) | 59 (5) | 70 (4) | 73 (4) | 1.2 (0.6 to 2.4), 0.583 | 1.2 (0.5 to 2.9), 0.685 | ||
Respiratory rate | 35 (4) | 70 (4) | 73 (4) | 45 (5) | 68 (4) | 79 (4) | 2.4 (1.1 to 5.0), 0.002 | 1.2 (0.4 to 3.1), 0.713 | ||
Pulse | 63 (4) | 76 (4) | 75 (4) | 60 (5) | 71 (4) | 80 (4) | 1.2 (0.6 to 2.5), 0.510 | 1.5 (0.6 to 4.1), 0.268 | ||
Oxygen saturation | 54 (5) | 76 (4) | 74 (4) | 57 (5) | 71 (4) | 80 (4) | 1.4 (0.7 to 2.9), 0.231 | 1.4 (0.5 to 3.6), 0.430 | ||
Routine investigations | ||||||||||
Urea and electrolytes | 99 (1) | 98 (1) | 99 (1) | 100 | 99 (1) | 100 | 0.6 (0.01 to 27.7), 0.762 | NA | ||
Chest x ray | 97 (2) | 98 (1) | 97 (2) | 97 (2) | 98 (1) | 100 | 0.7 (0.1 to 5.6), 0.641 | NA | ||
Full blood count | 98 (1) | 98 (1) | 99 (1) | 99 (1) | 99 (1) | 100 | 1.7 (0.1 to 40.4), 0.663 | NA |
NA=not applicable because of 100% in cells.
*After intervention.
†OR >1 favours SPI2. No items showed significant variation between hospitals within arms.